DPU - Symposium 2022

Medica l Image Ana lysis & Ar t i f icia l Intel l igence Symposium 2022 Nr. 10: Dipl.-Ing. Philipp Lazen, BSc: Comparing 7 T FID CRT MRSI with Amino Acid PET Curriculum Vitae: Dipl.-Ing. Philipp Lazen, BSc is a PhD student in his second year at the Medical University of Vienna. He works on MR spectroscopic imaging (MRSI). For his master thesis I developed a pulse simulation model which can be used to test different excitation pulses in a numerical phantom. His PhD focuses on various approaches towards improving MRSI, such as the application of higher order shim coils as well as post processing methods like B1 correction. Additionally, he is involved in various clinical studies involving clinical patients and healthy volunteers. As such, his work unites aspects of software development and coding, data science and analysis, and biology and medicine. Abstract: Comparing 7 T FID CRTMRSI with Amino Acid PET Magnetic resonance spectroscopic imaging (MRSI) and positron emission tomography (PET) are both imaging modalities capable of going beyond the mere structural contrasts delivered by other modalities, instead delivering information about metabolic processes in physiological and pathological tissues. To achieve this, MRSI uses the slightly different resonance frequencies that different metabolites have in an external magnetic field, and PET uses radioactively marked amino acids as tracers. Thus, both approaches can map the activity of cells, which is often elevated in tumors. Due to their similar nature, we decided to compare the results from our 7T MRSI with clinical PET scans in glioma patients. This poster is based on a publication which represented the first quantitative comparison of 7T MRSI and PET.